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Trial Search

Current Search Criteria:

Intervention: Esketamine hydrochloride (intranasal)

Found 11 matching trials

A Double-blind Study to Assess the Efficacy and Safety of Intranasal Esketamine for the Rapid Reduction of the Symptoms of Major Depressive Disorder, Including Suicidal Ideation, in Participants Who Are Assessed to be at Imminent Risk for Suicide

PHASE2

The purpose of this study is to evaluate the efficacy of intranasal esketam...

Status

Completed

Location

Multiple Locations

Start Date

2014-05-23

Trial ID

NCT02133001

Treatments Being Tested

Esketamine Placebo

Ketamine Safety and Tolerability in Psychiatric Inpatient Care (KetGD)

N/A

This observational registry aims to collect real-world data on ketamine use...

Status

Enrolling By Invitation

Location

Department of Psychiatry, Medical University of Gdańsk

Start Date

2022-09-01

Trial ID

NCT05565352

Treatments Being Tested

Ketamine Hydrochloride

Pharmacokinetic, Safety, and Tolerability Study of Intranasally Administered Esketamine in Elderly and and Healthy Younger Adult Participants

PHASE1

The purpose of this study is to compare the pharmacokinetics, safety, and t...

Status

Completed

Location

Multiple Locations

Start Date

2014-12

Trial ID

NCT02345148

Treatments Being Tested

Esketamine

Intranasal Dexmedetomidine or Esketamine for Negative Postoperative Behavioral Changes in Children

PHASE4

The goal of this clinical trial is to learn whether intranasal dexmedetomid...

Status

Not Yet Recruiting

Location

Children's Hospital of Nanjing Medical University

Start Date

2026-06-01

Trial ID

NCT07570160

Treatments Being Tested

Dexmedetomidine Esketamine Normal Saline

A Study to Evaluate the Efficacy, Safety, and Tolerability of Fixed Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

PHASE3

The purpose of this study is to compare the efficacy and safety of switchin...

Status

Completed

Location

Multiple Locations

Start Date

2015-08-10

Trial ID

NCT02417064

Treatments Being Tested

Esketamine Placebo Duloxetine (Oral Antidepressant)Escitalopram (Oral antidepressant)Sertraline (Oral Antidepressant)Venlafaxine Extended Release (XR) (Oral Antidepressant)

A Study of Intranasal Esketamine Plus an Oral Antidepressant for Relapse Prevention in Adult Participants With Treatment-resistant Depression

PHASE3

The purpose of this study is to assess the efficacy of intranasal esketamin...

Status

Completed

Location

Multiple Locations

Start Date

2015-10-01

Trial ID

NCT02493868

Treatments Being Tested

Esketamine Placebo Duloxetine (Oral Antidepressant)Escitalopram (Oral antidepressant)Sertraline (Oral Antidepressant)Venlafaxine Extended Release (XR) (Oral Antidepressant)

A Study to Evaluate the Efficacy, Safety, and Tolerability of Intranasal Esketamine Plus an Oral Antidepressant in Elderly Participants With Treatment-resistant Depression

PHASE3

The purpose of this study is to evaluate the efficacy and safety of switchi...

Status

Completed

Location

Multiple Locations

Start Date

2015-08-20

Trial ID

NCT02422186

Treatments Being Tested

Esketamine Placebo Duloxetine (Oral Antidepressant)Escitalopram (Oral Antidepressant)Sertraline (Oral Antidepressant)Venlafaxine Extended Release (XR) (New Antidepressant)

Esketamine With or Without Integration Therapy for Treatment-Resistant Depression

PHASE4

This study will explore the effects of esketamine (Spravato®), an FDA-appro...

Status

Recruiting

Location

Pravan Foundation

Start Date

2026-02-01

Trial ID

NCT07369102

Treatments Being Tested

Esketamine hydrochloride (intranasal)Integration Therapy

A Study to Evaluate the Efficacy, Safety, and Tolerability of Flexible Doses of Intranasal Esketamine Plus an Oral Antidepressant in Adult Participants With Treatment-resistant Depression

PHASE3

The purpose of this study is to compare the efficacy and safety of switchin...

Status

Completed

Location

Multiple Locations

Start Date

2015-08-07

Trial ID

NCT02418585

Treatments Being Tested

Esketamine Placebo Duloxetine (Oral Antidepressant)Escitalopram (Oral antidepressant)Sertraline (Oral Antidepressant)Venlafaxine Extended Release (XR) (Oral Antidepressant)

A Long-term, Safety and Efficacy Study of Intranasal Esketamine in Treatment-resistant Depression

PHASE3

The purpose of this open-label, multicenter study is to assess the long ter...

Status

Completed

Location

Multiple Locations

Start Date

2015-09-30

Trial ID

NCT02497287

Treatments Being Tested

Esketamine (Intranasal Spray)Duloxetine (Oral Antidepressant)Escitalopram (Oral Antidepressant)Sertraline (Oral Antidepressant)Venlafaxine Extended Release (XR) (Oral Antidepressant)

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